Prescriptions made by Humberto F Pavon

Data for 2018

7,933

Medicare Part D Prescriptions Filled, Including Refills

Rank: 292 out of 2,768 providers in this state and specialty

$746.7K

Total Retail Price of All Prescriptions

Rank: 177 out of 2,768 providers in this state and specialty

428

Patients Receiving at Least One Drug in Part D

Rank: 265 out of 2,768 providers in this state and specialty

86%

Patients 65 Years and Older

73

Average Age of Patients

Average age of patients for providers in this state and specialty is 71

Drug Categories

O

Opioid

An opioid drug. Prescription opioids (painkillers) can help alleviate certain kinds of pain in the short term but carry serious health risks.
A

Antibiotic

Used to treat bacterial infections but are often prescribed incorrectly to treat viral infections, such as chest colds or the flu.
P

Antipsychotic

Used to manage psychosis, principally in schizophrenia but also in a range of other psychotic disorders.

Prescription Data

The table below list this provider’s drugs, the number of prescriptions and how many went to seniors. Drugs are ranked by volume. Rank in State ranks all providers that have the self-identified specialty of Internal Medicine in Virginia and ranks the number of prescriptions that have been made for the specific drug.

Drug Name Rank in State Total Prescriptions Filled with Refills Prescript. to 65+ Patients Receiving this Drug Patients 65+ OAP
1 AMLODIPINE BESYLATE2210
of 1,5650
3120 prescriptions
Less than 1% of all prescriptions
2880730 patients
17% of all patients
< 11
2 LEVOTHYROXINE SODIUM2020
of 1,3480
2920 prescriptions
Less than 1% of all prescriptions
2420560 patients
13% of all patients
< 11
3 FUROSEMIDE1460
of 1,4210
2390 prescriptions
Less than 1% of all prescriptions
2140640 patients
15% of all patients
< 11
4 SIMVASTATIN1540
of 1,2170
2220 prescriptions
Less than 1% of all prescriptions
1610490 patients
11% of all patients
370 patients
9% of all patients
5 ATORVASTATIN CALCIUM3480
of 1,5960
2030 prescriptions
Less than 1% of all prescriptions
550 patients
13% of all patients
< 11
6 CARVEDILOL790
of 1,1640
1840 prescriptions
Less than 1% of all prescriptions
1670480 patients
11% of all patients
< 11
7 LOSARTAN POTASSIUM1900
of 1,3090
1810 prescriptions
Less than 1% of all prescriptions
1610430 patients
10% of all patients
< 11
8 OMEPRAZOLE2300
of 1,2070
1500 prescriptions
Less than 1% of all prescriptions
1190360 patients
8% of all patients
< 11
9 CLOPIDOGREL
(CLOPIDOGREL BISULFATE)
810
of 1,0630
1420 prescriptions
Less than 1% of all prescriptions
1420320 patients
7% of all patients
320 patients
7% of all patients
10 GABAPENTIN1760
of 1,2460
1640 prescriptions
Less than 1% of all prescriptions
1360420 patients
10% of all patients
< 11
11 ROSUVASTATIN CALCIUM870
of 1,0200
1400 prescriptions
Less than 1% of all prescriptions
350 patients
8% of all patients
< 11
12 LOSARTAN-HYDROCHLOROTHIAZIDE
(LOSARTAN/HYDROCHLOROTHIAZIDE)
670
of 8870
1280 prescriptions
Less than 1% of all prescriptions
990320 patients
7% of all patients
< 11
13 PANTOPRAZOLE SODIUM1260
of 1,2300
1390 prescriptions
Less than 1% of all prescriptions
1190380 patients
9% of all patients
< 11
14 PRAVASTATIN SODIUM1630
of 1,0720
1050 prescriptions
Less than 1% of all prescriptions
310 patients
7% of all patients
< 11
15 TAMSULOSIN HCL1260
of 1,0740
1120 prescriptions
Less than 1% of all prescriptions
350 patients
8% of all patients
< 11
16 METFORMIN HCL2430
of 1,2710
1080 prescriptions
Less than 1% of all prescriptions
950270 patients
6% of all patients
< 11
17 FINASTERIDE380
of 6780
960 prescriptions
Less than 1% of all prescriptions
260 patients
6% of all patients
< 11
18 LISINOPRIL3210
of 1,4860
1100 prescriptions
Less than 1% of all prescriptions
840270 patients
6% of all patients
< 11
19 METOPROLOL TARTRATE2190
of 1,2460
780 prescriptions
Less than 1% of all prescriptions
630230 patients
5% of all patients
< 11
20 ALLOPURINOL1010
of 9810
920 prescriptions
Less than 1% of all prescriptions
230 patients
5% of all patients
< 11
21 POTASSIUM CHLORIDE1500
of 9460
1090 prescriptions
Less than 1% of all prescriptions
830340 patients
8% of all patients
< 11
22 SPIRONOLACTONE440
of 7590
1100 prescriptions
Less than 1% of all prescriptions
920310 patients
7% of all patients
< 11
23 MONTELUKAST SODIUM1310
of 1,0150
820 prescriptions
Less than 1% of all prescriptions
670270 patients
6% of all patients
< 11
24 METOPROLOL SUCCINATE2090
of 1,2220
780 prescriptions
Less than 1% of all prescriptions
210 patients
5% of all patients
< 11
25 METFORMIN HCL ER
(METFORMIN HCL)
1010
of 7820
720 prescriptions
Less than 1% of all prescriptions
440180 patients
4% of all patients
< 11
26 NIFEDIPINE ER
(NIFEDIPINE)
120
of 4250
960 prescriptions
Less than 1% of all prescriptions
510180 patients
4% of all patients
< 11
27 RANITIDINE HCL1210
of 8510
620 prescriptions
Less than 1% of all prescriptions
160 patients
4% of all patients
< 11
28 SERTRALINE HCL1530
of 1,0110
690 prescriptions
Less than 1% of all prescriptions
180 patients
4% of all patients
< 11
29 EZETIMIBE410
of 5410
630 prescriptions
Less than 1% of all prescriptions
280130 patients
3% of all patients
< 11
30 AMITRIPTYLINE HCL250
of 5100
690 prescriptions
Less than 1% of all prescriptions
180 patients
4% of all patients
< 11
31 CHLORTHALIDONE420
of 4020
540 prescriptions
Less than 1% of all prescriptions
400180 patients
4% of all patients
< 11
32 WARFARIN SODIUM1420
of 8880
630 prescriptions
Less than 1% of all prescriptions
160 patients
4% of all patients
< 11
33 ENALAPRIL MALEATE250
of 3620
630 prescriptions
Less than 1% of all prescriptions
500180 patients
4% of all patients
< 11
34 LANTUS SOLOSTAR
(INSULIN GLARGINE,HUM.REC.ANLOG)
670
of 7130
590 prescriptions
Less than 1% of all prescriptions
200 patients
5% of all patients
< 11
35 LISINOPRIL-HYDROCHLOROTHIAZIDE
(LISINOPRIL/HYDROCHLOROTHIAZIDE)
1290
of 8400
350 prescriptions
Less than 1% of all prescriptions
120 patients
3% of all patients
< 11
36 ULTRA-FINE MINI PEN NEEDLE
(PEN NEEDLE, DIABETIC)
120
of 1920
390 prescriptions
Less than 1% of all prescriptions
210 patients
5% of all patients
< 11
37 FLUTICASONE PROPIONATE1430
of 1,0100
450 prescriptions
Less than 1% of all prescriptions
200 patients
5% of all patients
< 11
38 GLIPIZIDE-METFORMIN
(GLIPIZIDE/METFORMIN HCL)
30
of 360
540 prescriptions
Less than 1% of all prescriptions
170 patients
4% of all patients
< 11
39 HYDROCHLOROTHIAZIDE2520
of 1,2040
380 prescriptions
Less than 1% of all prescriptions
130 patients
3% of all patients
< 11
40 ISOSORBIDE MONONITRATE ER
(ISOSORBIDE MONONITRATE)
820
of 6280
460 prescriptions
Less than 1% of all prescriptions
340< 11< 11
41 LOVASTATIN910
of 5970
290 prescriptions
Less than 1% of all prescriptions
290< 11< 11
42 HYDRALAZINE HCL1080
of 7430
450 prescriptions
Less than 1% of all prescriptions
340160 patients
4% of all patients
< 11
43 LYRICA
(PREGABALIN)
510
of 5440
400 prescriptions
Less than 1% of all prescriptions
280110 patients
3% of all patients
< 11
44 SYNTHROID
(LEVOTHYROXINE SODIUM)
980
of 7060
400 prescriptions
Less than 1% of all prescriptions
< 11< 11
45 ESOMEPRAZOLE MAGNESIUM670
of 6030
310 prescriptions
Less than 1% of all prescriptions
< 11< 11
46 NADOLOL40
of 390
270 prescriptions
Less than 1% of all prescriptions
270< 11< 11
47 KLOR-CON M20
(POTASSIUM CHLORIDE)
430
of 3810
440 prescriptions
Less than 1% of all prescriptions
440130 patients
3% of all patients
130 patients
3% of all patients
48 CLONIDINE HCL620
of 6110
540 prescriptions
Less than 1% of all prescriptions
330130 patients
3% of all patients
< 11
49 CITALOPRAM HBR
(CITALOPRAM HYDROBROMIDE)
1300
of 7820
380 prescriptions
Less than 1% of all prescriptions
< 11< 11
50 LORAZEPAM1150
of 7510
610 prescriptions
Less than 1% of all prescriptions
610150 patients
4% of all patients
150 patients
4% of all patients
51 MELOXICAM1280
of 7120
350 prescriptions
Less than 1% of all prescriptions
120 patients
3% of all patients
< 11
52 GLIPIZIDE ER
(GLIPIZIDE)
560
of 4570
380 prescriptions
Less than 1% of all prescriptions
380< 11< 11
53 DULOXETINE HCL1360
of 8320
320 prescriptions
Less than 1% of all prescriptions
< 11< 11
54 TRAMADOL HCL1370
of 8980
730 prescriptions
Less than 1% of all prescriptions
200 patients
5% of all patients
< 11O
55 TRIAMTERENE-HYDROCHLOROTHIAZID
(TRIAMTERENE/HYDROCHLOROTHIAZID)
810
of 6480
420 prescriptions
Less than 1% of all prescriptions
< 11< 11
56 IRBESARTAN530
of 3050
270 prescriptions
Less than 1% of all prescriptions
< 11< 11
57 CALCITRIOL310
of 1390
270 prescriptions
Less than 1% of all prescriptions
270< 11< 11
58 TRAZODONE HCL1850
of 9890
250 prescriptions
Less than 1% of all prescriptions
< 11< 11
59 JANUVIA
(SITAGLIPTIN PHOSPHATE)
1020
of 7250
300 prescriptions
Less than 1% of all prescriptions
110 patients
3% of all patients
< 11
60 ATENOLOL1750
of 9920
160 prescriptions
Less than 1% of all prescriptions
160< 11< 11
61 VENTOLIN HFA
(ALBUTEROL SULFATE)
1040
of 8930
600 prescriptions
Less than 1% of all prescriptions
190 patients
4% of all patients
< 11
62 ATENOLOL-CHLORTHALIDONE
(ATENOLOL/CHLORTHALIDONE)
80
of 1060
390 prescriptions
Less than 1% of all prescriptions
270< 11< 11
63 MECLIZINE HCL570
of 4200
230 prescriptions
Less than 1% of all prescriptions
230110 patients
3% of all patients
110 patients
3% of all patients
64 LEVOCETIRIZINE DIHYDROCHLORIDE550
of 1790
220 prescriptions
Less than 1% of all prescriptions
< 11< 11
65 METOLAZONE230
of 1510
300 prescriptions
Less than 1% of all prescriptions
300< 11< 11
66 VERAPAMIL ER
(VERAPAMIL HCL)
420
of 3300
200 prescriptions
Less than 1% of all prescriptions
< 11< 11
67 BENAZEPRIL HCL660
of 3890
190 prescriptions
Less than 1% of all prescriptions
190< 11< 11
68 CARBAMAZEPINE ER
(CARBAMAZEPINE)
50
of 520
310 prescriptions
Less than 1% of all prescriptions
190110 patients
3% of all patients
< 11
69 DICYCLOMINE HCL370
of 2950
270 prescriptions
Less than 1% of all prescriptions
< 11< 11
70 ELIQUIS
(APIXABAN)
1450
of 8110
250 prescriptions
Less than 1% of all prescriptions
< 11< 11
71 VENLAFAXINE HCL ER
(VENLAFAXINE HCL)
810
of 5570
190 prescriptions
Less than 1% of all prescriptions
< 11< 11
72 COLCRYS
(COLCHICINE)
190
of 1210
230 prescriptions
Less than 1% of all prescriptions
110< 11< 11
73 DONEPEZIL HCL1570
of 7300
200 prescriptions
Less than 1% of all prescriptions
200< 11< 11
74 DICLOFENAC SODIUM1060
of 6920
180 prescriptions
Less than 1% of all prescriptions
< 11< 11
75 ONGLYZA
(SAXAGLIPTIN HCL)
80
of 660
220 prescriptions
Less than 1% of all prescriptions
220< 11< 11
76 PREMARIN
(ESTROGENS, CONJUGATED)
150
of 1050
170 prescriptions
Less than 1% of all prescriptions
< 11< 11
77 BUPROPION XL
(BUPROPION HCL)
730
of 4940
180 prescriptions
Less than 1% of all prescriptions
180< 11< 11
78 SINGLE USE SWAB
(ALCOHOL ANTISEPTIC PADS)
250
of 1080
120 prescriptions
Less than 1% of all prescriptions
120< 11< 11
79 COLESTIPOL HCL90
of 690
330 prescriptions
Less than 1% of all prescriptions
330< 11< 11
80 HYDROXYZINE HCL360
of 2390
240 prescriptions
Less than 1% of all prescriptions
240< 11< 11
81 DILTIAZEM 24HR ER (CD)
(DILTIAZEM HCL)
670
of 4810
210 prescriptions
Less than 1% of all prescriptions
210< 11< 11
82 ZOLPIDEM TARTRATE1150
of 7900
250 prescriptions
Less than 1% of all prescriptions
140< 11< 11
83 AMILORIDE HCL60
of 120
200 prescriptions
Less than 1% of all prescriptions
< 11< 11
84 TEMAZEPAM430
of 2920
280 prescriptions
Less than 1% of all prescriptions
280< 11< 11
85 ROPINIROLE HCL800
of 4000
120 prescriptions
Less than 1% of all prescriptions
120< 11< 11
86 GLIPIZIDE1330
of 6910
110 prescriptions
Less than 1% of all prescriptions
110< 11< 11
87 LABETALOL HCL380
of 2410
230 prescriptions
Less than 1% of all prescriptions
< 11< 11
88 VALSARTAN920
of 6530
170 prescriptions
Less than 1% of all prescriptions
< 11< 11
89 TIZANIDINE HCL860
of 3880
270 prescriptions
Less than 1% of all prescriptions
160< 11< 11
90 QUETIAPINE FUMARATE1220
of 5470
220 prescriptions
Less than 1% of all prescriptions
< 11< 11P
91 XARELTO
(RIVAROXABAN)
910
of 6360
240 prescriptions
Less than 1% of all prescriptions
240< 11< 11
92 IPRATROPIUM BROMIDE390
of 1700
140 prescriptions
Less than 1% of all prescriptions
140< 11< 11
93 LANTUS
(INSULIN GLARGINE,HUM.REC.ANLOG)
690
of 4670
180 prescriptions
Less than 1% of all prescriptions
180< 11< 11
94 METOCLOPRAMIDE HCL200
of 1530
300 prescriptions
Less than 1% of all prescriptions
130< 11< 11
95 SEVELAMER CARBONATE290
of 670
140 prescriptions
Less than 1% of all prescriptions
< 11< 11
96 BUMETANIDE740
of 3660
230 prescriptions
Less than 1% of all prescriptions
230< 11< 11
97 DIGOXIN590
of 2320
110 prescriptions
Less than 1% of all prescriptions
110< 11< 11
98 ULORIC
(FEBUXOSTAT)
210
of 1010
190 prescriptions
Less than 1% of all prescriptions
< 11< 11
99 PAROXETINE HCL850
of 5860
200 prescriptions
Less than 1% of all prescriptions
< 11< 11
100 BUSPIRONE HCL980
of 4680
190 prescriptions
Less than 1% of all prescriptions
190< 11< 11
101 COLCHICINE340
of 1970
130 prescriptions
Less than 1% of all prescriptions
< 11< 11
102 CARTIA XT
(DILTIAZEM HCL)
580
of 3760
170 prescriptions
Less than 1% of all prescriptions
170< 11< 11
103 ADVAIR DISKUS
(FLUTICASONE PROPION/SALMETEROL)
730
of 7250
170 prescriptions
Less than 1% of all prescriptions
< 11< 11
104 FLUOXETINE HCL1050
of 7070
160 prescriptions
Less than 1% of all prescriptions
160< 11< 11
105 ULTRA-FINE NANO PEN NEEDLE
(PEN NEEDLE, DIABETIC)
410
of 2640
150 prescriptions
Less than 1% of all prescriptions
< 11< 11
106 PROPRANOLOL HCL ER
(PROPRANOLOL HCL)
230
of 1790
200 prescriptions
Less than 1% of all prescriptions
200< 11< 11
107 CELECOXIB710
of 4620
180 prescriptions
Less than 1% of all prescriptions
< 11< 11
108 ANORO ELLIPTA
(UMECLIDINIUM BRM/VILANTEROL TR)
350
of 1450
130 prescriptions
Less than 1% of all prescriptions
130< 11< 11
109 DOXAZOSIN MESYLATE700
of 3910
150 prescriptions
Less than 1% of all prescriptions
150< 11< 11
110 JANUMET
(SITAGLIPTIN PHOS/METFORMIN HCL)
340
of 1990
190 prescriptions
Less than 1% of all prescriptions
< 11< 11
111 NIACIN ER
(NIACIN)
160
of 600
170 prescriptions
Less than 1% of all prescriptions
< 11< 11
112 NOVOLOG MIX 70-30 FLEXPEN
(INSULIN ASPART PROT/INSULN ASP)
290
of 1110
140 prescriptions
Less than 1% of all prescriptions
< 11< 11
113 GLIPIZIDE XL
(GLIPIZIDE)
250
of 710
110 prescriptions
Less than 1% of all prescriptions
< 11< 11
114 JANUMET XR
(SITAGLIPTIN PHOS/METFORMIN HCL)
220
of 820
150 prescriptions
Less than 1% of all prescriptions
< 11< 11
115 TRESIBA FLEXTOUCH U-200
(INSULIN DEGLUDEC)
280
of 840
150 prescriptions
Less than 1% of all prescriptions
< 11< 11
116 MEMANTINE HCL960
of 4540
120 prescriptions
Less than 1% of all prescriptions
120< 11< 11
117 DIAZEPAM700
of 4500
220 prescriptions
Less than 1% of all prescriptions
< 11< 11
118 LEVEMIR FLEXTOUCH
(INSULIN DETEMIR)
900
of 4120
110 prescriptions
Less than 1% of all prescriptions
110< 11< 11
119 CLONAZEPAM1120
of 6530
200 prescriptions
Less than 1% of all prescriptions
200< 11< 11
120 DEXILANT
(DEXLANSOPRAZOLE)
390
of 2270
160 prescriptions
Less than 1% of all prescriptions
160< 11< 11
121 FAMOTIDINE1130
of 6050
160 prescriptions
Less than 1% of all prescriptions
160< 11< 11
122 RENVELA
(SEVELAMER CARBONATE)
220
of 450
140 prescriptions
Less than 1% of all prescriptions
< 11< 11
123 SPIRIVA
(TIOTROPIUM BROMIDE)
720
of 4840
140 prescriptions
Less than 1% of all prescriptions
140< 11< 11
124 DOXYCYCLINE HYCLATE750
of 4250
110 prescriptions
Less than 1% of all prescriptions
< 11< 11A
125 TRADJENTA
(LINAGLIPTIN)
650
of 2420
150 prescriptions
Less than 1% of all prescriptions
150< 11< 11
126 PREDNISONE1810
of 1,1880
150 prescriptions
Less than 1% of all prescriptions
< 11< 11
127 VOLTAREN
(DICLOFENAC SODIUM)
320
of 2040
250 prescriptions
Less than 1% of all prescriptions
< 11< 11
128 PENTOXIFYLLINE140
of 320
110 prescriptions
Less than 1% of all prescriptions
< 11< 11
129 VALACYCLOVIR
(VALACYCLOVIR HCL)
250
of 3120
210 prescriptions
Less than 1% of all prescriptions
< 11< 11
130 INSULIN SYRINGE
(SYRINGE-NEEDLE,INSULIN,0.5 ML)
280
of 1450
120 prescriptions
Less than 1% of all prescriptions
120< 11< 11
131 MINOXIDIL140
of 310
110 prescriptions
Less than 1% of all prescriptions
110< 11< 11
132 PENTAZOCINE-NALOXONE HCL
(PENTAZOCINE HCL/NALOXONE HCL)
10
of 30
160 prescriptions
Less than 1% of all prescriptions
< 11< 11O
133 TRIAMCINOLONE ACETONIDE870
of 5480
110 prescriptions
Less than 1% of all prescriptions
< 11< 11
134 ACARBOSE140
of 250
110 prescriptions
Less than 1% of all prescriptions
110< 11< 11
135 LEVETIRACETAM1060
of 4190
130 prescriptions
Less than 1% of all prescriptions
< 11< 11
136 VENLAFAXINE HCL220
of 1310
180 prescriptions
Less than 1% of all prescriptions
180< 11< 11
137 CYCLOBENZAPRINE HCL940
of 5870
140 prescriptions
Less than 1% of all prescriptions
< 11< 11
138 ALPRAZOLAM2010
of 8260
130 prescriptions
Less than 1% of all prescriptions
130< 11< 11
139 LIDOCAINE-PRILOCAINE
(LIDOCAINE/PRILOCAINE)
90
of 260
130 prescriptions
Less than 1% of all prescriptions
< 11< 11
140 OLANZAPINE410
of 1850
250 prescriptions
Less than 1% of all prescriptions
< 11< 11P
141 SULFAMETHOXAZOLE-TRIMETHOPRIM
(SULFAMETHOXAZOLE/TRIMETHOPRIM)
580
of 4380
120 prescriptions
Less than 1% of all prescriptions
120< 11< 11A
142 PROAIR HFA
(ALBUTEROL SULFATE)
730
of 6270
150 prescriptions
Less than 1% of all prescriptions
150< 11< 11
143 PRAZOSIN HCL140
of 370
120 prescriptions
Less than 1% of all prescriptions
120< 11< 11
144 BETAMETHASONE VALERATE90
of 120
140 prescriptions
Less than 1% of all prescriptions
140< 11< 11
145 NITROGLYCERIN490
of 2650
140 prescriptions
Less than 1% of all prescriptions
< 11< 11
146 DESVENLAFAXINE SUCCINATE ER
(DESVENLAFAXINE SUCCINATE)
150
of 400
110 prescriptions
Less than 1% of all prescriptions
110< 11< 11
147 DILTIAZEM 24HR ER (LA)
(DILTIAZEM HCL)
50
of 50
110 prescriptions
Less than 1% of all prescriptions
110< 11< 11
148 ESTRADIOL370
of 2270
110 prescriptions
Less than 1% of all prescriptions
110< 11< 11
149 ISRADIPINE10
110 prescriptions
Less than 1% of all prescriptions
110< 11< 11
150 VALPROIC ACID
(VALPROIC ACID (AS SODIUM SALT))
280
of 440
110 prescriptions
Less than 1% of all prescriptions
00< 1100 patients
Less than 1% of all patients
151 IBUPROFEN870
of 4140
110 prescriptions
Less than 1% of all prescriptions
< 11< 11
152 ONDANSETRON HCL760
of 3420
110 prescriptions
Less than 1% of all prescriptions
110< 11< 11
153 CIPROFLOXACIN HCL730
of 6140
210 prescriptions
Less than 1% of all prescriptions
170 patients
4% of all patients
< 11A
154 CHLORHEXIDINE GLUCONATE280
of 710
140 prescriptions
Less than 1% of all prescriptions
00< 1100 patients
Less than 1% of all patients
155 AMOXICILLIN-CLAVULANATE POTASS
(AMOXICILLIN/POTASSIUM CLAV)
700
of 6750
180 prescriptions
Less than 1% of all prescriptions
180 patients
4% of all patients
< 11A
156 AZITHROMYCIN920
of 8330
380 prescriptions
Less than 1% of all prescriptions
370 patients
9% of all patients
< 11A
157 FLUCONAZOLE510
of 3560
140 prescriptions
Less than 1% of all prescriptions
< 11< 11
158 METHYLPREDNISOLONE660
of 3250
160 prescriptions
Less than 1% of all prescriptions
160130 patients
3% of all patients
130 patients
3% of all patients